Getting too stoned is uncomfortable, to say the least. There are products to mute this overstimulating experience. Still, for a long time, many claimed that taking cannabidiol (CBD) would do the same. The cannabinoid is believed to also amplify pain-relieving properties when added to THC products. Unfortunately, a research paper published by the American Society for Clinical Pharmacology & Toxicology refuted the merit of this method.
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This clinical trial sought to understand how CBD truly interacts with THC. Researchers regarded adverse effects and all to understand the pain-relieving potential of the cannabinoids.
Reshaping how we see CBD and THC work together
The randomized, double-blind, placebo-controlled trial engaged 37 healthy volunteers. One group was given nine milligrams (mg) of THC with a placebo CBD. Others received varying doses of true CBD. Either 10, 30, or 450 mg was administered orally. Researchers used intravenous (IV) sampling and various tests to monitor the pain relieving and stoney effects of the different cannabinoid ratios.
CBD failed to enhance pain relief at any dose, but it did have another statistically relevant impact. The group that received 450 mg felt higher on a subjective, cognitive, autonomous, and psychomotor level. Those who received 10 and 30 mg did not experience significantly different effects than the placebo group.
These findings indicate that adding CBD to cannabis product formulations may not reduce pain. In fact, it might not be the answer for those who have had too much THC. The findings pique interest, but the study was on a small scale with less than 40 patients.
Jumping from a dose of 30 to 450 mg of CBD leaves a lot of room for exploration. There could be potential pain relief or a point where the cannabinoid enhances a THC high. More research could make more sense of collected data as this study is the start rather than an answer.
Additional CBD research is always coming
Since its discovery, CBD has been a focus of research around the globe. Croatian researchers recently published their work on the quality of life CBD factors bring. What they found was that it can really take the edge off of the day.
This was a randomized crossover trial of 64 patients with hypertension. Each received five weeks of anywhere from 225 to 450 mg of CBD and five weeks of a placebo. Participants spent two weeks taking no cannabinoids between the two administration periods.
Patients used multiple self-reporting assessment tools to share about the quality of sleep, sleepiness during the day, potential memory issues, and general anxiety. After receiving the CBD, and not the placebo, patients mostly increased their sleepiness score.
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Everyone felt more bright-eyed and bushy-tailed throughout the day. Patients also recorded increased psychological well-being and vitality after five weeks of CBD.
Learning more about what CBD can do provides patients, brands, consumers, budtenders, and everyone in the cannabis sphere with more insight into how best to utilize the plant. These studies supply brushstrokes to the masterpiece of what this cannabinoid can do. Without more focused research, it is impossible to wholly know the power of the plant.
