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After two decades of practice and research with biochemists, Canadian doctor Andrew Kerklaan has developed topical formulas that offer pain relief paired with soothing botanical benefits. Dr. Kerklaan Therapeutics make use of the entire cannabis plant in skin creams and sticks — important because cannabis’s dozens of active ingredients are considered to work better in concert than in isolation. The robust product line is available in effect-based formulas – Pain, PMS, Sleep and Skin.